Cigarette smoking causes lung cancer, as well as cancers of the esophagus, larynx, mouth, throat, kidney, bladder, pancreas, stomach and cervix. Other tobacco products (such as smokeless tobacco, cigars and pipes) also increase cancer risk. Smoking is the leading cause of premature, preventable death in the U.S. and much of the world; 79,000 men and 56,000 women in the U.S. die annually from lung cancer caused by cigarette smoking. In addition, about 3,000 nonsmokers die from lung cancer each year in the U.S. due to secondhand smoke. If you use tobacco, quitting is by far the most important step you can take to protect your health. It is never too late to quit.